Alkaptonuria

Identifying joint-specific gait mechanisms causing impaired gait in alkaptonuria patients

Alkaptonuria is a rare genetic disease that leads to structural joint damage and impaired movement function. Previous research indicates that alkaptonuria affects gait, however the detailed mechanisms are unknown. Research question: What are the …

Age-Related Deviation of Gait from Normality in Alkaptonuria

Alkaptonuria is a rare metabolic disease leading to systemic changes including early and severe arthropathy which affects mobility. For unknown reasons, the onset of degenerative changes is delayed to around 30 years of age when both objective and …